Pengaruh Fasciolosis pada Sapi Bali Berdasarkan Pemeriksaan Darah, Serum Glutamic Pyruvic Transaminase (SGPT) dan Alkaline Phosphatase (ALP). (Effect of Fasciolosis on Bali Cattle to Serum Glutamic Pyruvic Transaminase (SGPT) and Alkaline Phosphatase (ALP).

AMIRULLAH, AMIRULLAH and Dradjad, Adji, S. and Made Sriasih, Sriasih and DEPAMEDE, SULAIMAN N and Djoko, Kisworo (2018) Pengaruh Fasciolosis pada Sapi Bali Berdasarkan Pemeriksaan Darah, Serum Glutamic Pyruvic Transaminase (SGPT) dan Alkaline Phosphatase (ALP). (Effect of Fasciolosis on Bali Cattle to Serum Glutamic Pyruvic Transaminase (SGPT) and Alkaline Phosphatase (ALP). Pengaruh Fasciolosis pada Sapi Bali Berdasarkan Pemeriksaan Darah, Serum Glutamic Pyruvic Transaminase (SGPT) dan Alkaline Phosphatase (ALP). (Effect of Fasciolosis on Bali Cattle to Serum Glutamic Pyruvic Transaminase (SGPT) and Alkaline Phosphatase (ALP, 36 (2). pp. 247-253. ISSN ISSN 0126-0421 (Print), ISSN 2407-3733 (Online)

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Abstract

Investation of Fasciola sp. On several species of cattle in Indonesia has occurred since a long time ago. Fasciolosis caused a high economical loss such as decreasing of carcass and organs, sometimes caused death of calves. The objectives of the research were to evaluate the effect of fasciolosis on Serum Glutamic Pyruvic Transaminase (SGPT), and the obstruction of bile duct by Alkaline Phosphatase (ALP) in Bali cattle suffered from fasciolosis. Faeces of Bali cattle raised in endemic areas of fasciolosis were examinated by sedimentation test to identify eggs per gram of faeces (EPG) of Fasciola sp. The blood samples of cattle which positive to fasciolosis were use to study the hematology by autoanalyser, SGPT and ALP. The results of research showed that from 89 cattle, 28 were infected by Fasciola sp. whithin of 7-115 EPG (min-max). From 20 fasciolosis cattle were indicated that MCHC of 90%, RBC of 30%, HB of 20%, and eosinophils of 2 % of cattle were lower than that of normal standard, while lymphocytes of 60%, MCV of 40%, ALP of 10% and SGPT of 5% of cattle were higher than that of normal standard. hematological appearances of cattle suffered from fasciolosis had macrocytichypochromic anemia, eosinopenia, and lymphocytosis. The increase of SGPT may be caused byhepatic cells destruction by young liver flukes, and the increase of ALP was caused by the obstruction of bile duct by mature liver flukes. Infestasi cacing Fasciola sp. pada berbagai jenis sapi di Indonesia telah lama terjadi. Fasciolosis menyebabkan banyak kerugian ekonomi berupa penurunan kualitas karkas dapat menyebabkan kematian pada sapi muda. Tujuan dari penelitian ini adalah untuk mengetahui perubahan hematologi, Serum Glutamic Pyruvic Transaminase (SGPT), Alkaline Phosphatase (ALP) pada sapi Bali yang menderita fasciolosis. Sapi Bali yang dipelihara didaerah endemis fasciolosis diperiksa fesesnya menggunakan metode sedimentasi untuk mengetahui telur cacing per gram tinja/eggs per gram of faeces (EPG). Sapi yang terdeteksi positif diambil darahnya untuk dievaluasi hematologi menggunakan autoanalyser. Serum glutamic pyruvic transaminase (SGPT) diperiksa menggunakan ILab 300 Plus Chemistry System dan Alkaline phosphatase (ALP) menggunakan IL 300 Plus Chemistry. Hasil pemeriksaan EPG menunjukkan bahwa feses dari 89 ekor, 28 ekor terinfeksi cacing Fasciola sp. mengandung 7-115 EPG (min-maks), dari 20 ekor sapi diperoleh indikasi masing-masing 90% Mean corpuscular hemoglobin concentration (MCHC), 30% red blod cells (RBC), 20% haemoglobin (Hb), dan 2% eosinofil dibawah strandar normal, kebalikannya 60% limfosit, 40% mean corpuscular value (MCV), 10% ALP dan 5% SGPT terdeteksi berada diatas standar normal. Sapi penderita fasciolosis mengalami anemia makrositik hipokromik, eosinopenia, limfositosis. Kenaikan SGPT menunjukkan kerusakan hati oleh cacing muda, kenaikan ALP juga diduga karena adanya penyumbatan duktus biliverus oleh cacing dewasa.

Item Type:	Article
Keywords (Kata Kunci):	Cattle; Fasciolosis; Hematology; SGPT; ALP; Fasciolosis; Hematologi; Sapi; SGPT; ALP
Subjects:	S Agriculture > SF Animal culture
Divisions:	Fakultas Peternakan
Depositing User:	Ir Djoko Kisworo, M.Sc., Ph.D
Date Deposited:	17 Oct 2021 23:56
Last Modified:	17 Oct 2021 23:56
URI:	http://eprints.unram.ac.id/id/eprint/25020

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