Maskur, Maskur and Rodiah, Rodiah and Arman, Chairussyuhur (2014) Association of Novel Single nucleotide Polymorphism in Growth hormone receptor gene with production traits in Bali cattle. Italian Journal of Animal Science, 13 (4). pp. 841-844. ISSN 1594-4077
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Abstract
The growth hormone (GH) is the main regulator of postnatal growth and metabolism in mammals. The action of GH on target cells depends on the growth hormone receptor (GHR). This is mediated through induced transcription of other genes. GHR gene is one of the candidate genes employed in selection strategy using DNA markers (marker assisted selection). This study was designed to identify the novel single nucleotide polymorphisms (SNPs) in exon 8 and intron 8 of GHR gene that may affect production traits in Bali cattle. A SNP was identified by the direct sequencing technique. Genotypes of the SNPs were identified using PCR-RFLP. The SNP was located in intron 8 of the GHR gene and was caused by an A/G transition. It was identified using the HpyCH4III restriction enzyme. Polymorphism of GHR/HpyCH4III has a significant influence on weaning weight and average daily gain, but not on birth weight of Bali cattle.
| Item Type: | Article |
|---|---|
| Keywords (Kata Kunci): | Gene, Mutation, Restriction, Polymorphism, Bali cattle |
| Subjects: | S Agriculture > S Agriculture (General) |
| Divisions: | Fakultas Peternakan |
| Depositing User: | Relanti Saleha |
| Date Deposited: | 02 Jan 2023 03:14 |
| Last Modified: | 02 Jan 2023 03:14 |
| URI: | http://eprints.unram.ac.id/id/eprint/34151 |
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Association of Novel Single nucleotide Polymorphism in Growth hormone receptor gene with production traits in Bali cattle. (deposited 26 Dec 2022 05:54)
- Association of Novel Single nucleotide Polymorphism in Growth hormone receptor gene with production traits in Bali cattle. (deposited 02 Jan 2023 03:14) [Currently Displayed]
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