Antimicrobial Assay and GC-MS Analysis of Leaves Extracts Medicinal Plant Senna hirsuta (L.)

Hidayati, Ernin and Wardani, Istana and Susyanti, Devi and Mardianti, Silmi and Sudarma, I Made (2020) Antimicrobial Assay and GC-MS Analysis of Leaves Extracts Medicinal Plant Senna hirsuta (L.). Antimicrobial Assay and GC-MS Analysis of Leaves Extracts Medicinal Plant Senna hirsuta (L.), 11 (3). pp. 215-219. ISSN 0975-8585

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Abstract

The antimicrobial assay and gas chromatography mass spectrometry (GC-MS) analyses of Senna hirsuta leaves extracts in two different solvents polarity that is n-hexane and dichloromethane were evaluated against bacterial and fungal namely Escherichia coli, Salmonella typhi, Candida albicans and Fusarium oxysporum. The n-hexane extract exhibited significant antibacterial and antifungal activities against the pathogen and not found for dichloromethane extract. The moderate antimicrobial activity found at 60% concentration of n-hexane extract with zone of inhibition about 9.6 mm in diameter. Chemical constituents of the n-hexane extract was separated and identified by means of GC-MS analyses permitted the identification of 9 constituents. The main components of the n-hexane extract were citronellal (10.82%), ar-turmerone (20.71 %), tumerone (18.75 %), hexadecanoate acid (3.99%), phytol (19.47 %), oxacycloheptadec-8-en-2-one (5.34 %) and isomer of oxacycloheptadec-8-en-2-one (5.28%).

Item Type: Article
Keywords (Kata Kunci): Senna hirsuta (L.); antimicrobial; GC-MS, Escherichia coli, Salmonella typhi, Candida albicans and Fusarium oxysporum
Subjects: Q Science > Q Science (General)
Q Science > QR Microbiology
Divisions: Fakultas Matematika dan ilmu Pengetahuan Alam
Depositing User: Dr. ERNIN HIDAYATI
Date Deposited: 14 Apr 2023 07:28
Last Modified: 14 Apr 2023 07:28
URI: http://eprints.unram.ac.id/id/eprint/36398

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