Lestari, Rina and Ajmala, Indana Eva and Fathana, Prima Belia and Pintaningrum, Yusra (2022) Jurnal - Study of SARS-COV 2 Antibody Level Before and After the Third Covid-19 Vaccine Booster on Health Worker in Province of Nusa Tenggara Barat General Hospital. Advances in Health Sciences Research, 46. pp. 371-377. ISSN 2468-5739
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Abstract
Vaccination is one of the ways that countries around the world to manage the COVID-19. The effectiveness of a vaccine can be assessed from the degree of protective antibodies produced after the vaccination program. The purpose of this study was to determine the levels of SARS-CoV-2 antibodies in the sixth month after two doses of CoronaVac immunization and one month after MRNA-1273 vaccine immunization and to determine the relationship between age, sex, nutritional status, smoking habits and exercise habits on antibody levels in research subjects. Observational research with a cross sectional approach. The sample in this study were health workers who had received COVID-19 immunization who met the inclusion criteria and were taken using a purposive sampling technique. Then the data obtained will be analyzed descriptively using the SPSS program. A total of 29 subjects (51.72% women) participated in this study. The mean age of the research subjects was 35.71 years. The results of the antibody titer examination 6 months after the second dose of CoronaVac immunization (before MRNA-1273 vaccine immunization) showed the lowest antibody titer was 2.17 U/ml and the highest was > 250 U/ml, while the antibody titer 1 month after MRNA1273 vaccine immunization showed > 250 U/ml in all subjects. The results of the correlation test showed that there were no significant results regarding the relationship between antibody levels 6 months after CoronaVac immunization with age (r= -0.282, p=0.139), gender (r= -0.095, p=0.623), nutritional status (r = 0.007, p = 0.973), smoking habits (r = 0.082, p = 0.672), and exercise habits (r = -0.243, p = 0.204). The levels of antibodies in the sixth month after the second dose of CoronaVac immunization were still detected in the range of 2.17 to > 250 U/ml, while the levels of SARS CoV-2 antibodies in the first month after the MRNA-1273 vaccine immunization all reached the upper limit of the examination. The levels of SARS-CoV-2 antibodies in the sixth month after the second dose of CoronaVac immunization were not significantly related to age, sex, nutritional status, smoking habits and exercise habits
| Item Type: | Article |
|---|---|
| Keywords (Kata Kunci): | COVID-19, Vaccine, Antibody. |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Fakultas Kedokteran |
| Depositing User: | dr Rina Lestari Sp.P |
| Date Deposited: | 30 May 2023 03:19 |
| Last Modified: | 30 May 2023 03:19 |
| URI: | http://eprints.unram.ac.id/id/eprint/38976 |
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