Yuanita, Emmy and Jannah, Baiq Khaeratul and Ulfa, Maria and SUDIRMAN, SUDIRMAN and NINGSIH, BAIQ NILA SARI and Dharmayani, Ni Komang Tri (2023) C-prenylation of 1,3 dihydroxyxanthone: synthesis, characterization and antibacterial activity. Acta Chemica Asiana, 6 (1). pp. 279-286. ISSN 2550-0503
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Abstract
Prenylated 1,3-dihydroxyxanthone has been successfully synthesized using Prenyl bromide and KOH. Characterization of the synthesized compound using Infra Red (IR) and Nuclear Magnetic Resonance (1H-NMR) showed that monosubstituted c-prenylation was occurred at carbon number 2 to form 1,3-dihydroxy-2-prenylxanthone. The synthesis result was a yellow-brown paste with a yield of 43.09%. This prenylated 1,3-dihydroxyxanthone had moderate antibacterial activity against Escherichia coli with an inhibition zone > 5 mm at a concentration of 15%.
Item Type: | Article |
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Subjects: | Q Science > QD Chemistry |
Divisions: | Fakultas Matematika dan ilmu Pengetahuan Alam |
Depositing User: | Dr. EMMY YUANiTA, S.Si, M.Si |
Date Deposited: | 09 Jun 2023 02:37 |
Last Modified: | 09 Jun 2023 02:37 |
URI: | http://eprints.unram.ac.id/id/eprint/39535 |
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