CFD SIMULATION OF PLASMA LEAKAGE AND FLUID FLOW ON DENGUE VIRUS INFECTED-ENDOTHELIAL CELLS

Nur, Kaliwantoro (2016) CFD SIMULATION OF PLASMA LEAKAGE AND FLUID FLOW ON DENGUE VIRUS INFECTED-ENDOTHELIAL CELLS. CFD SIMULATION OF PLASMA LEAKAGE AND FLUID FLOW ON DENGUE VIRUS INFECTED-ENDOTHELIAL CELLS, 11 (2). pp. 1021-1024. ISSN 1819-6608

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Abstract

Plasma leakage is one of the pathological features in dengue infection and may cause fatal condition to the patients. In this study, the investigations of the plasme leakage and fluid flow around the dengue virus infected-endothelial cells were conducted using computational fluid dynamic (CFD) based on in vitro experiments of HUVEC (human umbilical vein endothelial cell) culture on the permeable membrane. Fluid velocity profiles and wall shear stress (WSS) values were computed in each surface of endothelial cells. Fluid flow was assumed as a fully developed incompressible Newtonian flow. It was shown that the leakage flow occurs due to the increase in the gap between the cell-cell junctions of the dengue virus-infected cells. The peaks of the wall shear stress distribution occur at the cell’s tip, where the cell-c

Item Type: Article
Keywords (Kata Kunci): Simulation, plasma leakage, dengue
Subjects: T Technology > T Technology (General)
Divisions: Fakultas Teknik
Depositing User: Dr Nur Kaliwantoro ST.MT
Date Deposited: 29 Jun 2023 04:49
Last Modified: 29 Jun 2023 04:49
URI: http://eprints.unram.ac.id/id/eprint/40523

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