THE DIFFERENCES OF BACTERIAL SENSITIVITY IN CHRONIC SUPPURATIVE OTITIS MEDIA TOWARDS METRONIDAZOLE AND CHLORAMPHENICOL

Wardhani, Meylinda Komala and Kadriyan, Hamsu and Wiguna, Putu Aditya (2013) THE DIFFERENCES OF BACTERIAL SENSITIVITY IN CHRONIC SUPPURATIVE OTITIS MEDIA TOWARDS METRONIDAZOLE AND CHLORAMPHENICOL. S1 thesis, Universitas Mataram.

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Abstract

Background: Chronic suppurative otitis media (CSOM) is an inflammation of the middle ear caused by fluid accumulation behind the ear drum as a result of obstruction of the eustachius tube. COSM is an ear infection disease that has a prevalence and a public health problem in developing countries and developed countries. In 2002, it was estimated that 503,269 people in Indonesia had a hearing impairment caused by CSOM and become second largest cause of hearing loss in Indonesia. The purpose of this study was to determine the bacteria that cause CSOM and their sensitivity bacteria to antibiotics metronidazole and chloramphenicol. Method: The non-experimental study with analytical cross-sectional study design in patients with CSOM is conducted in this reserach. Samples obtained from out patients ENT department West Nusa Tenggara Hospital. The middle ear isolate from patients who was diagnosed with CSOM were taken, then cultured procedure was done with bacterial culture medium and followed by antibiotic sensitivity testing. Analysis of differences in sensitivity of both antibiotics were used Chi-square test if eligible, if not eligible then used absolute test of Fisher. Results: The most common bacteria that were found in this study were Pseudomonas aeruginosa. The results showed that the sensitivity of the bacteria in CSOM had a low senstifity to both antibiotics. Antibiotic sensitivity is mild to Staphylococcus aureus, the bacteria are still sensitive to chloramphenicol, but not sensitive to metronidazole. The results of statistical tests found that the alternative hypothesis is rejected and the null hypothesis accepted. Conclusion: Antibiotics metronidazole sensitivity was not different compared with chloramphenicol.

Item Type: Thesis (S1)
Keywords (Kata Kunci): chronic suppurative otitis media, sensitivity, metronidazole, chloramphenicol, bacteria.
Subjects: R Medicine > R Medicine (General)
R Medicine > RF Otorhinolaryngology
Divisions: Fakultas Kedokteran
Depositing User: Hamsu Kadriyan
Date Deposited: 30 May 2018 04:50
Last Modified: 30 May 2018 04:50
URI: http://eprints.unram.ac.id/id/eprint/4446

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